MEDICAL HYPOTHESES AND RESEARCH
VOL. 4, No. 2, July 2008




G. D. Li [2008] Med. Hypotheses Res. 1: 69‒73.


Pfcrmp May Play a Key Role in Chloroquine
Antimalarial Action and Resistance Development




Gao-De Li*

School of Biological Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom



Abstract. It was proposed earlier that Pfcrmp (Plasmodium falciparum chloroquine
resistance marker protein) may be the chloroquine target protein in nucleus. In this
communication, further evidence is presented to support the view that Pfcrmp may play a
key role in chloroquine antimalarial actions as well as resistance development.




Correspondence: Dr. Gao-De Li, School of Biological Sciences, University of
Liverpool, Liverpool L69 7ZB, United Kingdom.
E-Mail: gaode@liverpool.ac.uk



Full Text PDF